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・ Retiniphyllum concolor
・ Retinite
・ Retinitis
・ Retinitis pigmentosa
・ Retinitis pigmentosa GTPase regulator
・ Retinitis Pigmentosa International
・ Retinitus
・ Retinne
・ Retinoblastoma
・ Retinoblastoma protein
・ Retinoblastoma-like protein 1
・ Retinoblastoma-like protein 2
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・ Retinoic acid
Retinoic acid receptor
・ Retinoic acid receptor alpha
・ Retinoic acid receptor beta
・ Retinoic acid receptor gamma
・ Retinoic acid syndrome
・ Retinoic acid-inducible orphan G protein-coupled receptor
・ Retinoid
・ Retinoid receptor
・ Retinoid X receptor
・ Retinoid X receptor alpha
・ Retinoid X receptor beta
・ Retinoid X receptor gamma
・ Retinol
・ Retinol binding protein
・ Retinol binding protein 4


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Retinoic acid receptor : ウィキペディア英語版
Retinoic acid receptor

The retinoic acid receptor (RAR) is a type of nuclear receptor which can also act as a transcription factor that is activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-alpha, RAR-beta, and RAR-gamma, encoded by the , , genes, respectively. Each receptor isoform has several splice variants: two- for alpha, four- for beta, and two- for gamma.
As with other type II nuclear receptors, RAR heterodimerizes with RXR and in the absence of ligand, the RAR/RXR dimer binds to hormone response elements known as retinoic acid response elements (RAREs) complexed with corepressor protein. Binding of agonist ligands to RAR results in dissociation of corepressor and recruitment of coactivator protein that, in turn, promotes transcription of the downstream target gene into mRNA and eventually protein.
==See also==

*Retinoid receptor
* Retinoid X receptor

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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